Prolotherapy involves a series of injections, reportedly ranging from 3 to 30 (average 4 to 10), depending on the pain condition and the individual being treated. The prolotherapy injection series may cover 3 to 6 months with injections at 2 to 3 week intervals. Most patients require about 4 to 6 prolotherapy treatments to restore function and relieve pain, but many find improvement after only one session.

How long does it take to work?

Possible side effects may last a few days to a couple weeks and include swelling, intense pain and stiffness, headache, allergic reaction.

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PRP or platelet rich plasma is an injection procedure using the patient's own concentrated platelets, stem cells and growth factors from their own blood. The injection of PRP to an injured area delivers growth factors concentrated from five to ten times greater than is normally found in plasma. The compound is prepared through withdrawal of blood from the patient, centrifugation to increase the concentration, and then injected into the area that was damaged or injured.

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What are the side effects?

How many treatments do I need?

Prolotherapy is an injection procedure used to treat connective tissue injuries of the musculoskeletal system that have not healed by either rest or other nonsurgical therapies in order to relieve back pain. The injections promote a healing response in small tears and weakened tissue, with the goal of alleviating back pain and improving function.

What are the side effects?

Using stem cell therapy or tissue engineering, physicians expect that patients will achieve a number of different benefits, including: faster recovery time following the procedure, improvements in joint, ligaments, and tendon function, no significant incisions or trauma to the area, very little pain or discomfort during the procedure, no general anesthesia, renewal and repair within the joint, very low side effect profile and little risk of allergy or adverse reaction.

The Prolotherapy technique involves the injection of a proliferant (a mild irritant solution – dextrose, phenol, glycerin, or sodium morrhuate, a purified derivative of cod liver oil) that causes an inflammatory response which stimulates the healing process. A local anesthetic is used so there is minimal discomfort with the injections.

What is injected?

Approximately two to four treatments depending on the degree of injury and how long the injury has been there. Typically injections are performed every 6 weeks.

What is Prolotherapy?

For the first 48 hours, swelling and mild discomfort are typical in the injected area. Therefore, all patients are provided with pain medicine after PRP. Minimal side effects have been observed with treatment. Any stiffness or discomfort reported after PRP should resolve with time.By day 3, these symptoms will begin to substantially resolve.

Most patients notice some element of improvement by 2-6 weeks after PRP treatment. Symptom improvement is slow and subtle as days and weeks pass, with usual report of original pain being lessened over time. Increased endurance and strength are typically reported.

What are the benefits of Regenerative Medicine over traditional therapies?

What is PRP?

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Frequently Asked Questions about Regenerative Medicine

How many injections do I need?